All about AMH (ANTI MULLERIAN HORMONE)
1. What is AMH?
(AMH) Anti Mullerian Hormone is produced by the small egg sacs (follicles) in the ovaries which contain the egg. Production of AMH decreases and then stops as follicles grow.
2. What do AMH levels signify?
Since AMH is produced only in small egg sacs which are not visible on ultrasound, blood levels of AMH give us an idea about the size of pool of small follicles in woman’s ovaries, i.e. remaining egg supply or ovarian reserve.
3. On which day of the cycle, the AMH test should be done and what are the normal levels of AMH?
AMH levels are fairly constant and the testing can be done on any day of the woman’s cycle. There are different commercial assays for doing this test and different units are used in different countries to denote the results (ng/ml or pmol/L). So sometimes the results from different laboratories might not be comparable.
4. What happens to AMH levels with age?
As the number of follicles in the ovary decreases with age, there is a decrease in AMH levels.
5. What are the factors which may affect AMH levels?
Factors which may affect the levels of AMH include-
- Age of women
- Polycystic Ovarian Syndrome( PCOS)
- Ovarian Surgery
- Contraceptive Hormones
- High TSH levels
- Low Vitamin D3 Levels
- Ovarian Radiation
- Ovarian Chemotherapy
- Premature Ovarian Failure
6. What is the relation between AMH levels and chances of pregnancy with In-vitro Fertilization (IVF)?
Women with AMH values in high or normal range tend to have a better chance of having a good number of eggs retrieved with IVF. This can help in allowing a large number of embryos to be developed. But still, the egg quality depends more on the age of the woman and not on the AMH levels. So younger women with lower AMH levels tend to have better quality eggs than older women with normal AMH levels leading to good chances of pregnancy with IVF (In-vitro Fertilization).