In this procedure, husband semen/donor semen is washed to remove the debris, pus cells & bacteria & is placed inside the uterine cavity by a special catheter (Insemination cannula).
The process is painless, easy & an OPD procedure. It requires no sedation or anesthesia.
The ovaries are gently stimulated with oral tablets either alone or with low dose hormone injections followed by ultrasound monitoring until the follicles are mature when HCG trigger is given. The aim is to stimulate the release of one or two eggs only. Insemination is performed around the time of ovulation.
It increases the chances of pregnancy as the semen quality is improved by washing, the quality of egg is improved by medicine & the timing of insemination is set with the ovulation.
The success rate with this procedure is in the range of 10 – 15 % and 3 – 6 cycles are generally advocated before proceeding to higher ART forms.
Factors influencing outcome of IUI:
- Age and duration of infertility
- Semen quality
- Indication of IUI
- Ovarian stimulation protocol
- Semen preparation
- Timing of IUI
- Technique of IUI
- Number of inseminations
Indications of IUI:
- Anovulatory infertility
- Unexplained infertility
- Azoospermia (nil sperms)
- Cervical factor
- Male factor